Prime® is the complete and concentrated conditioner for both fresh and saltwater. Prime® removes chlorine, chloramine and detoxifies ammonia, nitrite, and nitrate. It is non-acidic and will not impact pH. A further bonus for the reef hobbyist—Prime® will not over-activate skimmers. Prime® may be used during tank cycling to alleviate ammonia/nitrite toxicity. It contains a binder which renders ammonia, nitrite, and nitrate nontoxic, allowing the bio-filter to more efficiently remove them. It will also detoxify any heavy metals found in the tap water at typical concentration levels. Use at start-up and whenever adding or replacing water.